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KMID : 0605820130200010001
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Korean Journal of Pediatric Infectious Diseases
2013 Volume.20 No. 1 p.1 ~ p.8
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Clinical Manifestations of Salmonellosis in Children during the last 12 Years:A Single Institution Experience
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Park Jae-Hong
Lee Taek-Jin
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Abstract
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Purpose : The purpose of this study is to investigate the clinical manifestations and antibiotic resistance of salmonellosis in children.
Methods : We reviewed medical records and investigated the clinical characteristics of culture-proven childhood salmonellosis from January 2000 through December 2011 at the CHA Bundang Medical center.
Results : We assessed 53 patients. The median age was 3-years-old (minimum 12 days, maximum 18-years-old) and the number of male patients was 33 (62.3%). It occurred most frequently in the summer (39%) and in 2001 (11 cases) however there was no case in 2009 and 2010. Salmonella typhi was isolated in 3 cases with septicemia. Antibiotic resistance to ampicillin was most frequently presented (30.2%) and 63.6% in serogroup B. No antibiotics resistance strains were cultured in patients with positive Salmonella typhi. Admitted patients from 2000 to 2011 were divided into 2 groups; group 1 from 2000 to 2005 and group 2 from 2006 to 2011. 40 cases belonged to group 1 and 13 cases were in the group 2. Group 2 showed more resistance to ampicillin than group 1 but without any statistical significance(25% vs. 38.5%, P =0.349). In group 1, the most common serotype was group D and in group 2, the most common serotype were group C and D.
Conclusion : Salmonellosis in children was frequently occurred from 2000 to 2003 but decreased after 2004. There was no difference in clinical manifestations, serotypes and antibiotic resistances between the years.
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KEYWORD
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Salmonellosis, Antibiotics resistance, Children
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